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Megalis 20 mg may also be prescribed for benign prostatic hyperplasia (BPH, enlarged prostate) and pulmonary arterial hypertension (PAH), where it helps ease urinary difficulty and reduce pressure in the lung arteries, respectively. It is usually taken once per day, about 30–60 minutes before sexual activity, and its effect can last up to about 36 hours, allowing more flexibility in timing intercourse. Megalis 20 mg is a tadalafil‑based tablet used mainly to treat erectile dysfunction (ED) in adult men. It contains 20 mg of tadalafil, a phosphodiesterase‑5 (PDE‑5) inhibitor that relaxes blood vessels in the penis, improving blood flow so men can achieve and maintain a firm erection during sexual stimulation.