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Vilitra is a prescription medicine used to treat erectile dysfunction (ED) in adult men. It contains vardenafil, a PDE5 inhibitor that helps improve blood flow to the penis during sexual stimulation. It works by blocking the enzyme phosphodiesterase type 5 (PDE5), which increases levels of cyclic guanosine monophosphate (cGMP). This relaxes smooth muscles in the corpus cavernosum of the penis, allowing increased blood flow during sexual arousal. As a result, it helps achieve and maintain an erection, but only when sexual stimulation is present. It does not cause an erection on its own.